Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.47 |
| ▸ | SKP1 | P63208 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64557 | 0.84 | NPC1 (0.47) | ALDH1A1L3MBTL1KDM4ESCD | |
| SCHEMBL938175 | 0.84 | CKS1B (0.50) | CKS1BSKP1SKP2SMOSCD | |
| SCHEMBL937452 | 0.84 | NPC1 (0.43) | BPTFALDH1A1L3MBTL1KDM4ESCD | |
| SCHEMBL2944404 | 0.83 | NPC1 (0.46) | ALDH1A1HSD17B10GFERKDM4EHPGD | |
| SCHEMBL938850 | 0.81 | MEN1 (0.52) | BPTFALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL20255223 | 0.81 | BPTF (0.60) | BPTFAOC3DPP4CKS1BSKP1 | |
| SCHEMBL936603 | 0.81 | SLC6A7 (0.55) | DPP4CKS1BSKP1SKP2SMO | |
| SCHEMBL936568 | 0.80 | SIGMAR1 (0.42) | BPTFALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL23960997 | 0.80 | GPR119 (0.53) | CKS1BSKP1SKP2MAP4K4ALDH1A1 | |
| SCHEMBL938002 | 0.80 | LMNA (0.48) | HSD17B10GAAL3MBTL1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149618-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |