Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.58 |
| ▸ | NNMT | P40261 | 1/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12143427 | 0.81 | KDM4E (0.72) | GABRA5KDM4EMAPTMMP13POLB | |
| SCHEMBL7660982 | 0.80 | POLB (0.56) | KDM4EMMP13POLBHPGDHTT | |
| SCHEMBL18715411 | 0.80 | HCAR3 (0.70) | HCAR3NNMTMAPTHPGDHTT | |
| SCHEMBL10032058 | 0.79 | HCAR3 (0.49) | HCAR3NNMTKDM4EMAPTPOLB | |
| SCHEMBL14000515 | 0.79 | NNMT (0.51) | HCAR3NNMTKDM4EMAPTPOLB | |
| SCHEMBL1308966 | 0.79 | POLB (0.50) | GABRA5KDM4EMMP13POLBHPGD | |
| SCHEMBL28773428 | 0.79 | POLB (0.50) | GABRA5KDM4EMMP13POLBHPGD | |
| SCHEMBL20255504 | 0.79 | POLB (0.50) | GABRA5KDM4EMMP13POLBHPGD | |
| SCHEMBL29127177 | 0.78 | EPHX2 (0.63) | NNMTGABRA5KDM4EMMP13POLB | |
| SCHEMBL19835593 | 0.78 | EPHX2 (0.63) | GABRA5KDM4EMMP13POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |