Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291420 | 0.81 | GABRP (0.45) | SMN1; SMN2GRIA2USP2ALDH1A1MEN1 | |
| SCHEMBL20037822 | 0.81 | GRIA2 (0.36) | SMN1; SMN2TSHRGRIA2USP2ATM | |
| SCHEMBL21267701 | 0.80 | KMT2A (0.36) | SMN1; SMN2GRIA2USP2ALDH1A1MEN1 | |
| SCHEMBL12673011 | 0.79 | TAS2R14 (0.48) | NAMPT | |
| SCHEMBL21193218 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRALDH1A1NAMPTGAA | |
| SCHEMBL20249183 | 0.79 | ALDH1A1 (0.40) | SMN1; SMN2TSHRGRIA2USP2ALDH1A1 | |
| SCHEMBL18291549 | 0.79 | GRIA2 (0.38) | SMN1; SMN2GRIA2USP2ALDH1A1MEN1 | |
| SCHEMBL12910012 | 0.77 | CHRNB2 (0.53) | SMN1; SMN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL12880767 | 0.76 | CHRNB2 (0.62) | ALDH1A1NAMPT | |
| SCHEMBL10192138 | 0.76 | ALDH1A1 (0.49) | TSHRGRIA2ATMALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022236253-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| WO-2022236256-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |