Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20037908 | 0.83 | L3MBTL1 (0.50) | KDM4ERAD52PAX8CD274DRD4 | |
| SCHEMBL20037937 | 0.81 | HRH4 (0.39) | KDM4ELMNATDP1HRH4HRH3 | |
| SCHEMBL23105108 | 0.75 | L3MBTL1 (0.47) | KDM4ELMNARAD52PAX8TDP1 | |
| SCHEMBL23105182 | 0.74 | LMNA (0.59) | KDM4ELMNARAD52PAX8TDP1 | |
| SCHEMBL12976234 | 0.73 | KDM4E (0.48) | KDM4ELMNARAD52PAX8TDP1 | |
| SCHEMBL14747737 | 0.73 | KDM4E (0.48) | KDM4ELMNARAD52PAX8TDP1 | |
| SCHEMBL14036603 | 0.72 | KDM4E (0.72) | KDM4ELMNARAD52PAX8S1PR2 | |
| SCHEMBL14213771 | 0.71 | KDM4E (0.39) | KDM4ELMNARAD52PAX8S1PR2 | |
| SCHEMBL20255422 | 0.71 | CHRNB2 (0.37) | LMNAHRH4HRH3L3MBTL1 | |
| SCHEMBL14182593 | 0.70 | KDM4E (0.38) | KDM4ELMNARAD52PAX8TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |