SCHEMBL6902908

SCHEMBL6902908

C[Si](Br)(Br)C1CC2C=CC1C2

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904497 0.86 KDM4E (0.35) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL4602316 0.81 KDM4E (0.33) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL3267075 0.81 KDM4E (0.33) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL200393 0.77 KDM4E (0.32) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL6836633 0.77 KDM4E (0.35) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL6063967 0.76 KDM4E (0.31) KDM4EALDH1A1LMNA
SCHEMBL7113258 0.76 KDM4E (0.31) KDM4EALDH1A1LMNA
SCHEMBL2605522 0.74 KDM4E (0.30) KDM4EALDH1A1
SCHEMBL6697237 0.74 KDM4E (0.37) KDM4EALDH1A1
SCHEMBL6063915 0.74 KDM4E (0.30) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040242782-A1 Rubber composition and vulcanized rubber SUMITOMO CHEMICAL COMPANY, LIMITED 2004-12-02 US disclosed