SCHEMBL6904497

SCHEMBL6904497

C[Si](C)(Br)C1CC2C=CC1C2

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6902908 0.86 KDM4E (0.32) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL3267075 0.86 KDM4E (0.33) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL6836633 0.82 KDM4E (0.35) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL16773667 0.81 KDM4E (0.33) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL4602316 0.81 KDM4E (0.33) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL200393 0.77 KDM4E (0.32) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL201645 0.77 KDM4E (0.32) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL6063967 0.76 KDM4E (0.31) KDM4ELMNAALDH1A1
SCHEMBL7113258 0.76 KDM4E (0.31) KDM4ELMNAALDH1A1
SCHEMBL8961503 0.75 KDM4E (0.39) KDM4ELMNAALDH1A1GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1572831-A Rubber composition and vulcanized rubber SUMITOMO CHEMICAL CO (JP) 2005-02-02 CN disclosed
US-20040242782-A1 Rubber composition and vulcanized rubber SUMITOMO CHEMICAL COMPANY, LIMITED 2004-12-02 US disclosed