Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20039943 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR3AACHE | |
| SCHEMBL16938591 | 0.89 | SLC6A3 (0.56) | SLC6A2SLC6A4SLC6A3HTR3ACHRNA7 | |
| SCHEMBL12066159 | 0.83 | ACHE (0.35) | SLC6A2SLC6A4SLC6A3ACHEGRIA4 | |
| SCHEMBL20039945 | 0.83 | ACHE (0.35) | SLC6A2SLC6A4SLC6A3ACHEGRIA4 | |
| SCHEMBL18215079 | 0.83 | ACHE (0.35) | SLC6A2SLC6A4SLC6A3ACHEGRIA4 | |
| SCHEMBL20039942 | 0.81 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL17690421 | 0.81 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL20039937 | 0.81 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL17150940 | 0.81 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL12065057 | 0.77 | HTR2C (0.41) | SLC6A2SLC6A4SLC6A3PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091012-B1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | CENTREXION THERAPEUTICS CORP (US) | 2018-04-11 | — | — | EP | disclosed |