Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 15/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11921811 | 0.91 | FOLH1 (0.41) | NPC1RAB9AFOLH1KMT2A | |
| SCHEMBL19149703 | 0.82 | MMP2 (0.52) | NPC1RAB9AFOLH1 | |
| SCHEMBL11545905 | 0.80 | NAAA (0.57) | NPC1RAB9AFOLH1 | |
| SCHEMBL18057035 | 0.80 | LMNA (0.47) | NPC1RAB9AALDH1A1 | |
| SCHEMBL13531590 | 0.76 | HDAC1 (0.56) | NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL11545678 | 0.76 | NAAA (0.55) | NPC1RAB9AFOLH1POLB | |
| SCHEMBL31344538 | 0.73 | NPC1 (0.63) | NPC1RAB9AFOLH1KMT2A | |
| SCHEMBL19130735 | 0.71 | MMP2 (0.50) | NPC1RAB9AFOLH1 | |
| SCHEMBL17002063 | 0.71 | CA12 (0.50) | NPC1RAB9AFOLH1 | |
| SCHEMBL7390854 | 0.71 | KDM4E (0.55) | FOLH1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673259-B1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2018-04-11 | — | — | EP | disclosed |