Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 10/20 | 0.37 |
| ▸ | GABRD | O14764 | 10/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 10/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 10/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 10/20 | 0.37 |
| ▸ | GABRE | P78334 | 10/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 10/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 10/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 10/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16562807 | 0.84 | CES2 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7185488 | 0.83 | TSHR (0.45) | TSHRMAPK1NR2E1KIF11PTPN5 | |
| SCHEMBL19060896 | 0.81 | POLB (0.41) | MAPK1GABRA1GABRB2KIF11ALDH1A1 | |
| SCHEMBL23717347 | 0.77 | FFAR4 (0.34) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16483011 | 0.77 | RAPGEF4 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL130383 | 0.77 | TSHR (0.56) | TSHRMAPK1NR2E1KIF11PTPN5 | |
| SCHEMBL9495189 | 0.77 | ALDH1A1 (0.40) | TSHRMAPK1ALDH1A1MAPTNOS3 | |
| SCHEMBL28102919 | 0.77 | ALDH1A1 (0.40) | TSHRMAPK1ALDH1A1MAPTNOS3 | |
| SCHEMBL394717 | 0.77 | TSHR (0.56) | TSHRMAPK1NR2E1KIF11PTPN5 | |
| SCHEMBL22546678 | 0.75 | NOTUM (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864289-B1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTED AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | CB THERAPEUTICS INC (KY) | 2018-04-11 | — | — | EP | disclosed |