SCHEMBL20041412

SCHEMBL20041412

Cc1ccccc1-c1cccnc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KMT2A Q03164 1/20 0.44
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
TACR1 P25103 2/20 0.40
PLAU P00749 1/20 0.40
MITF O75030 1/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
KDM4E B2RXH2 1/20 0.40
SLC6A2 P23975 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2592408 0.84 TDP1 (0.44) L3MBTL1KMT2ASMN1; SMN2GAAKDM4E
SCHEMBL632115 0.80
SCHEMBL30827699 0.80
SCHEMBL29594708 0.78 RIPK1 (0.47) L3MBTL1NPC1RAB9ASMN1; SMN2CASP3
SCHEMBL28545758 0.78 RIPK1 (0.47) L3MBTL1NPC1RAB9ASMN1; SMN2CASP3
SCHEMBL9963986 0.78 NOS3 (0.46) L3MBTL1KMT2ANOS3NOS1NOS2
Ammonia Solution, Strong SCHEMBL1678128 0.78
Water SCHEMBL6362161 0.78
SCHEMBL28309616 0.77 PTPRC (0.50) L3MBTL1KMT2ANOS3NOS1NOS2
SCHEMBL28410854 0.76 L3MBTL1 (0.52) L3MBTL1KMT2ANOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2982676-B1 Benzimidazo[2,1-B]benzoxazoles for electronic applications IDEMITSU KOSAN CO (JP) 2018-04-11 EP disclosed