Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18701466 | 0.89 | SMN1; SMN2 (0.33) | SMN1; SMN2LMNACYP17A1CYP3A4CYP19A1 | |
| SCHEMBL18701468 | 0.88 | LMNA (0.32) | SMN1; SMN2LMNACYP17A1CYP3A4CYP19A1 | |
| SCHEMBL20041768 | 0.83 | KDM4E (0.40) | SMN1; SMN2LMNATSHRKDM4EPIK3CA | |
| SCHEMBL26528200 | 0.81 | NQO2 (0.39) | SMN1; SMN2LMNATSHRRAB9AKDM4E | |
| SCHEMBL25592448 | 0.80 | TSHR (0.45) | SMN1; SMN2LMNATSHRNPC1RAB9A | |
| SCHEMBL24451575 | 0.76 | TSHR (0.39) | SMN1; SMN2LMNACYP17A1CYP3A4CYP19A1 | |
| SCHEMBL24451574 | 0.76 | TSHR (0.41) | SMN1; SMN2LMNACYP17A1CYP3A4CYP19A1 | |
| SCHEMBL20041733 | 0.76 | ALOX5 (0.46) | SMN1; SMN2LMNAKDM4E | |
| SCHEMBL24451573 | 0.76 | LMNA (0.40) | SMN1; SMN2LMNACYP17A1CYP3A4CYP19A1 | |
| SCHEMBL24452006 | 0.72 | THRB (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |