Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 20/20 | 0.59 |
| ▸ | FPR1 | P21462 | 17/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015872 | 0.84 | FPR2 (0.61) | FPR2FPR1CYP3A4 | |
| SCHEMBL20041836 | 0.82 | FPR2 (0.62) | FPR2FPR1 | |
| SCHEMBL18264179 | 0.81 | FPR2 (0.72) | FPR2FPR1CYP3A4 | |
| SCHEMBL18264180 | 0.81 | FPR2 (0.72) | FPR2FPR1CYP3A4 | |
| SCHEMBL21995818 | 0.78 | FPR2 (0.73) | FPR2FPR1CYP3A4 | |
| SCHEMBL19559563 | 0.77 | FPR2 (0.55) | FPR2FPR1 | |
| SCHEMBL19559510 | 0.77 | FPR2 (0.55) | FPR2FPR1 | |
| SCHEMBL22016004 | 0.77 | FPR2 (0.55) | FPR2FPR1 | |
| SCHEMBL28993773 | 0.77 | FPR2 (0.55) | FPR2FPR1 | |
| SCHEMBL18106453 | 0.77 | FPR2 (0.55) | FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305763-A1 | DEUTERATED OR ISOTOPICALLY LABELED UREA DERIVATIVES OR PHARMACOLOGICALLY ACCEPTABLE SALTS THEREOF USEFUL AS FPRL-1 AGONISTS | Kyorin Pharmaceutical Co., Ltd. (JP) | 2018-04-11 | — | — | EP | disclosed |