SCHEMBL20042556

SCHEMBL20042556

COC(=O)/C(=C\C(F)(F)F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
MAPT P10636 1/20 0.35
TET2 Q6N021 1/20 0.31
CES2 O00748 1/20 0.31
ACHE P22303 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5532962 1.00 ALDH1A1 (0.35) ALDH1A1MAPTTET2CES2ACHE
SCHEMBL775665 0.81
SCHEMBL18655700 0.81 ALDH1A1 (0.37) ALDH1A1MAPTTET2CES2ACHE
SCHEMBL21848009 0.81
SCHEMBL6203909 0.78 DGAT1 (0.30)
SCHEMBL6203910 0.78 DGAT1 (0.30)
SCHEMBL28097615 0.77 NPSR1 (0.39) ALDH1A1MAPTCES2ACHECES1
SCHEMBL4009654 0.76 ALDH1A1 (0.35) ALDH1A1MAPTTET2
SCHEMBL71370 0.74 ALDH1A1 (0.39) ALDH1A1MAPTTET2
SCHEMBL11938107 0.74 ALDH1A1 (0.36) ALDH1A1MAPTTET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018065350-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2018-04-12 WO disclosed