Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042556 | 0.81 | ALDH1A1 (0.35) | ALDH1A1MAPTTET2CES2ACHE | |
| SCHEMBL5532962 | 0.81 | ALDH1A1 (0.35) | ALDH1A1MAPTTET2CES2ACHE | |
| SCHEMBL28944264 | 0.78 | — | — | |
| SCHEMBL27618248 | 0.78 | — | — | |
| SCHEMBL27757791 | 0.78 | MAPT (0.41) | ALDH1A1MAPTTET2MEN1XBP1 | |
| SCHEMBL28109999 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TET2KEAP1NFE2L2HCAR2 | |
| SCHEMBL22296704 | 0.76 | — | — | |
| SCHEMBL5644945 | 0.75 | GLO1 (0.47) | ALDH1A1MAPTCES2ACHECES1 | |
| SCHEMBL27648818 | 0.75 | GLO1 (0.47) | ALDH1A1MAPTCES2ACHECES1 | |
| SCHEMBL13858138 | 0.74 | ALDH1A1 (0.32) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170084839-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170084839-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | PPOX, OSTC, OCIAD1 | ALDH1A1 2904/4885MAPT 80/4885TET2 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.