Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | PRLHR | P49683 | 10/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042751 | 0.84 | HSD17B10 (0.49) | HSD17B10GBA1KMT2AMEN1POLB | |
| SCHEMBL20042687 | 0.83 | HSD17B10 (0.51) | HSD17B10GBA1KMT2AMEN1POLB | |
| SCHEMBL20042810 | 0.82 | HSD17B10 (0.46) | HSD17B10GBA1PRLHRKMT2AMEN1 | |
| SCHEMBL20042811 | 0.82 | HSD17B10 (0.60) | HSD17B10GBA1KMT2AMEN1POLB | |
| SCHEMBL20042740 | 0.81 | HSD17B10 (0.49) | HSD17B10GBA1KMT2AMEN1POLB | |
| SCHEMBL20042711 | 0.80 | HSD17B10 (0.50) | HSD17B10GBA1KMT2AMEN1POLB | |
| SCHEMBL20042827 | 0.79 | HSD17B10 (0.46) | HSD17B10GBA1PRLHRKMT2AMEN1 | |
| SCHEMBL20042719 | 0.79 | HSD17B10 (0.46) | HSD17B10GBA1KMT2AMEN1POLB | |
| SCHEMBL20042812 | 0.79 | HSD17B10 (0.46) | HSD17B10GBA1PRLHRKMT2AMEN1 | |
| SCHEMBL20042980 | 0.78 | LSS (0.50) | HSD17B10GBA1PRLHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |