Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042795 | 0.89 | HPGD (0.46) | PDE10ANTSR1HSD11B1GPR6 | |
| SCHEMBL20042722 | 0.88 | ALDH1A1 (0.43) | KMT2AMGLLNTSR1MEN1HSD11B1 | |
| SCHEMBL20042687 | 0.85 | HSD17B10 (0.51) | HSD17B10KMT2AMGLLMAPTGBA1 | |
| SCHEMBL20042725 | 0.85 | PDE2A (0.41) | MGLLPDE10APROKR1NTSR1 | |
| SCHEMBL20042811 | 0.84 | HSD17B10 (0.60) | HSD17B10KMT2AGBA1MEN1POLB | |
| SCHEMBL20042751 | 0.83 | HSD17B10 (0.49) | HSD17B10KMT2AMGLLGBA1MEN1 | |
| SCHEMBL20042824 | 0.81 | PROKR1 (0.40) | HSD17B10KMT2AMGLLPDE10AMAPT | |
| SCHEMBL20042711 | 0.81 | HSD17B10 (0.50) | HSD17B10KMT2AMAPTGBA1MEN1 | |
| SCHEMBL20042740 | 0.80 | HSD17B10 (0.49) | HSD17B10KMT2AMAPTGBA1MEN1 | |
| SCHEMBL20042827 | 0.80 | HSD17B10 (0.46) | HSD17B10KMT2AMGLLGBA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |