Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 10/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042821 | 0.92 | MEN1 (0.41) | MEN1KMT2AIDH1P2RX7KDM4E | |
| SCHEMBL20042886 | 0.89 | HPGD (0.49) | KMT2AIDH1P2RX7HPGDTSHR | |
| SCHEMBL20042752 | 0.89 | HPGD (0.47) | MEN1KMT2AP2RX7HPGDTSHR | |
| SCHEMBL20042696 | 0.88 | KDM1A (0.45) | MEN1KMT2AP2RX7KDM4EHPGD | |
| SCHEMBL20042903 | 0.88 | MEN1 (0.42) | MEN1KMT2AP2RX7KDM4EHPGD | |
| SCHEMBL20042754 | 0.86 | MEN1 (0.41) | MEN1KMT2AP2RX7KDM4EHPGD | |
| SCHEMBL20042667 | 0.86 | TACR3 (0.46) | P2RX7 | |
| SCHEMBL20042887 | 0.86 | GPR6 (0.42) | P2RX7HPGDTSHRALDH1A1 | |
| SCHEMBL20042698 | 0.85 | MEN1 (0.43) | MEN1KMT2AP2RX7KDM4EHPGD | |
| SCHEMBL20042728 | 0.85 | MEN1 (0.42) | MEN1KMT2AALDH1A1L3MBTL1FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |