Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 8/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042721 | 0.88 | GRM5 (0.47) | MEN1KMT2ASLC6A7PDE2AL3MBTL1 | |
| SCHEMBL20042817 | 0.88 | PKM (0.44) | MEN1KMT2AALDH1A1SLC6A7GBA1 | |
| SCHEMBL20043028 | 0.86 | KDM4E (0.40) | MEN1KMT2AALDH1A1FASNL3MBTL1 | |
| SCHEMBL20042903 | 0.86 | MEN1 (0.42) | MEN1KMT2AALDH1A1FASNL3MBTL1 | |
| SCHEMBL20042685 | 0.85 | HTT (0.42) | SLC6A7L3MBTL1GBA1EPHX2 | |
| SCHEMBL20042751 | 0.85 | HSD17B10 (0.49) | MEN1KMT2AALDH1A1GBA1 | |
| SCHEMBL20042839 | 0.85 | P2RX7 (0.45) | MEN1KMT2AALDH1A1L3MBTL1GBA1 | |
| SCHEMBL20042754 | 0.85 | MEN1 (0.41) | MEN1KMT2AALDH1A1FASNL3MBTL1 | |
| SCHEMBL20042713 | 0.85 | GRM5 (0.45) | MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL20042656 | 0.85 | KDM4E (0.37) | MEN1KMT2AALDH1A1FASNL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |