Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042752 | 0.94 | HPGD (0.47) | HPGDP2RX7TSHRKMT2ATACR3 | |
| SCHEMBL20042887 | 0.93 | GPR6 (0.42) | HPGDP2RX7TSHRGPR6TDP1 | |
| SCHEMBL20042792 | 0.91 | TACR3 (0.46) | HPGDP2RX7KMT2AGPR6TACR3 | |
| SCHEMBL20042667 | 0.91 | TACR3 (0.46) | P2RX7HTR1ATACR3 | |
| SCHEMBL20042821 | 0.89 | MEN1 (0.41) | HPGDP2RX7TSHRKMT2AIDH1 | |
| SCHEMBL20042733 | 0.89 | MEN1 (0.41) | HPGDP2RX7TSHRKMT2AIDH1 | |
| SCHEMBL20042680 | 0.89 | GPR6 (0.44) | HPGDP2RX7TSHRKMT2AGPR6 | |
| SCHEMBL20042880 | 0.88 | P2RX7 (0.40) | HPGDPKMP2RX7KMT2AIDH1 | |
| SCHEMBL20042884 | 0.88 | P2RX7 (0.40) | HPGDPKMP2RX7KMT2AIDH1 | |
| SCHEMBL20042751 | 0.88 | HSD17B10 (0.49) | HPGDP2RX7KMT2ATACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |