Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 18/20 | 0.43 |
| ▸ | PDE4A | P27815 | 16/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 16/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042990 | 0.86 | CNR1 (0.37) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20042828 | 0.81 | CHRM3 (0.40) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20042864 | 0.78 | HSD17B10 (0.39) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20042858 | 0.77 | ALDH1A1 (0.37) | CHRM4 | |
| SCHEMBL20042927 | 0.75 | TACR2 (0.40) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20042991 | 0.75 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL20042731 | 0.70 | CHRM3 (0.51) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20042979 | 0.68 | ALDH1A1 (0.42) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20042885 | 0.67 | PIP5K1C (0.38) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20042875 | 0.65 | PDE10A (0.35) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |