Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042929 | 0.87 | LMNA (0.42) | KMT2ATP53THRBTDP1LMNA | |
| SCHEMBL20042851 | 0.79 | P2RX7 (0.46) | HSD17B10GBA1KMT2ATP53THRB | |
| SCHEMBL20042982 | 0.79 | P2RX7 (0.46) | HSD17B10GBA1KMT2ATP53THRB | |
| SCHEMBL20042798 | 0.79 | TACR3 (0.42) | HSD17B10GBA1KMT2ALMNATACR3 | |
| SCHEMBL20042910 | 0.72 | P2RX7 (0.42) | HSD17B10GBA1KMT2ATP53THRB | |
| SCHEMBL20042904 | 0.72 | P2RX7 (0.42) | HSD17B10GBA1KMT2ATP53THRB | |
| SCHEMBL20042751 | 0.70 | HSD17B10 (0.49) | HSD17B10GBA1KMT2ALMNATACR3 | |
| SCHEMBL20042835 | 0.70 | HSD17B10 (0.41) | HSD17B10GBA1KMT2ATP53TACR3 | |
| SCHEMBL20042727 | 0.68 | TACR3 (0.47) | TACR3KCNH2TACR1P2RX7 | |
| SCHEMBL20042878 | 0.68 | TACR3 (0.47) | TACR3KCNH2TACR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |