Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 9/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042869 | 0.84 | PROKR1 (0.41) | PROKR1CNR1P2RX7GBA1SMN1; SMN2 | |
| SCHEMBL20042926 | 0.84 | HPGD (0.40) | CNR1CNR2GPR55P2RX7LMNA | |
| SCHEMBL20042973 | 0.83 | GPR6 (0.39) | CNR1CNR2GPR55P2RX7LMNA | |
| SCHEMBL20042798 | 0.82 | TACR3 (0.42) | P2RX7GBA1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL20043038 | 0.81 | TACR3 (0.47) | P2RX7 | |
| SCHEMBL20042872 | 0.79 | P2RX7 (0.44) | PROKR1CNR1CNR2GPR55P2RX7 | |
| SCHEMBL20042925 | 0.72 | PDE10A (0.36) | SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL20042742 | 0.71 | PROKR1 (0.35) | PROKR1P2RX7GBA1SMN1; SMN2HSD17B10 | |
| SCHEMBL21212469 | 0.69 | GAA (0.57) | PROKR1LMNA | |
| SCHEMBL12294710 | 0.69 | PROKR1 (0.63) | PROKR1SMN1; SMN2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |