Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 18/20 | 0.47 |
| ▸ | TACR2 | P21452 | 12/20 | 0.47 |
| ▸ | TACR1 | P25103 | 9/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042973 | 0.90 | GPR6 (0.39) | TACR3TACR2TACR1KCNH2P2RX7 | |
| SCHEMBL20042926 | 0.89 | HPGD (0.40) | TACR3TACR2TACR1KCNH2P2RX7 | |
| SCHEMBL20042798 | 0.86 | TACR3 (0.42) | TACR3TACR2TACR1KCNH2P2RX7 | |
| SCHEMBL20042878 | 0.85 | TACR3 (0.47) | TACR3TACR2TACR1KCNH2PDE2A | |
| SCHEMBL20042727 | 0.85 | TACR3 (0.47) | TACR3TACR2TACR1KCNH2PDE2A | |
| SCHEMBL20042902 | 0.81 | PROKR1 (0.41) | P2RX7 | |
| SCHEMBL20042792 | 0.79 | TACR3 (0.46) | TACR3TACR2TACR1KCNH2PDE2A | |
| SCHEMBL20042852 | 0.77 | TACR3 (0.47) | TACR3TACR2TACR1KCNH2PDE2A | |
| SCHEMBL20042983 | 0.74 | GPR6 (0.39) | TACR3TACR2TACR1KCNH2P2RX7 | |
| SCHEMBL20042883 | 0.74 | GPR6 (0.39) | TACR3TACR2TACR1KCNH2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |