Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 2/20 | 0.48 |
| ▸ | TDP2 | O95551 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 2/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GALK1 | P51570 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | CHRNA10 | Q9GZZ6 | 5/20 | 0.42 |
| ▸ | CHRNA9 | Q9UGM1 | 5/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 7/20 | 0.42 |
| ▸ | S100A4 | P26447 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876610 | 0.77 | APAF1 (0.74) | DNMT1APAF1TDP2NSD2HKDC1 | |
| SCHEMBL31290245 | 0.77 | APAF1 (0.74) | DNMT1APAF1TDP2NSD2HKDC1 | |
| SCHEMBL17249923 | 0.76 | DNMT1 (0.64) | DNMT1APAF1TDP2NSD2HKDC1 | |
| SCHEMBL249168 | 0.76 | APAF1 (0.77) | DNMT1APAF1TDP2NSD2HKDC1 | |
| SCHEMBL31290115 | 0.76 | APAF1 (0.77) | DNMT1APAF1TDP2NSD2HKDC1 | |
| SCHEMBL247037 | 0.73 | KMT2A (0.79) | DNMT1APAF1TDP2NSD2HKDC1 | |
| SCHEMBL246623 | 0.73 | DNMT1 (0.59) | DNMT1APAF1TDP2NSD2HKDC1 | |
| SCHEMBL10115432 | 0.69 | CHRNA7 (1.00) | CHRNA7MEN1KMT2ACHRNA10CHRNA9 | |
| SCHEMBL4649553 | 0.66 | DNMT1 (0.83) | DNMT1APAF1TDP2NSD2HKDC1 | |
| SCHEMBL14566963 | 0.65 | DNMT1 (0.56) | DNMT1APAF1TDP2NSD2HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180099917-A1 | REVERSIBLY REDUCIBLE MATERIALS AND USE THEREOF | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099917-A1 | REVERSIBLY REDUCIBLE MATERIALS AND USE THEREOF | NES, CBR3, SQOR | CHRNA7 2796/4885DNMT1 258/4885APAF1 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.