Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | NSD2 | O96028 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CDC25B | P30305 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31171425 | 0.84 | MEN1 (0.55) | ALDH1A1MAPTRAB9APOLBNSD2 | |
| SCHEMBL29967684 | 0.80 | HKDC1 (0.51) | ALDH1A1MAPTRAB9APOLBNSD2 | |
| SCHEMBL10615443 | 0.79 | AURKA (0.50) | AURKAAURKBALDH1A1MAPTRAB9A | |
| SCHEMBL20046959 | 0.78 | HKDC1 (0.50) | ALDH1A1MAPTRAB9APOLBNSD2 | |
| SCHEMBL868107 | 0.77 | MAOA (0.56) | AURKAAURKBALDH1A1MAPTPOLB | |
| 2,3-Dibromo-1,4-Naphthoquinone SCHEMBL1240837 | 0.77 | MAPT (0.68) | AURKAAURKBALDH1A1MAPTRAB9A | |
| 2,3-Dibromo-1,4-Naphthoquinone SCHEMBL29475349 | 0.77 | MAPT (0.68) | AURKAAURKBALDH1A1MAPTRAB9A | |
| SCHEMBL31290114 | 0.75 | IDO1 (0.60) | ALDH1A1MAPTRAB9APOLBNSD2 | |
| SCHEMBL2462086 | 0.75 | IDO1 (0.60) | ALDH1A1MAPTRAB9APOLBNSD2 | |
| Anthraquinone SCHEMBL27847594 | 0.71 | CDC25B (0.75) | ALDH1A1MAPTRAB9APOLBNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118932351-A | Electrochemical tandem preparation and application of antibacterial compound 2-amino quinone | 温州医科大学附属口腔医院 | 2024-11-12 | — | — | CN | disclosed |
| US-20180099917-A1 | REVERSIBLY REDUCIBLE MATERIALS AND USE THEREOF | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099917-A1 | REVERSIBLY REDUCIBLE MATERIALS AND USE THEREOF | NES, CBR3, SQOR | AURKA 1212/4885AURKB 1867/4885ALDH1A1 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.