Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CDC25B | P30305 | 4/20 | 0.50 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NSD2 | O96028 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.48 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31171425 | 0.95 | MEN1 (0.55) | HKDC1MEN1KMT2ACDC25BMALT1 | |
| SCHEMBL2462086 | 0.85 | IDO1 (0.60) | HKDC1MEN1KMT2ACDC25BMALT1 | |
| SCHEMBL31290114 | 0.85 | IDO1 (0.60) | HKDC1MEN1KMT2ACDC25BMALT1 | |
| SCHEMBL20046959 | 0.84 | HKDC1 (0.50) | HKDC1MEN1KMT2ACDC25BMALT1 | |
| SCHEMBL20043032 | 0.80 | AURKA (0.55) | HKDC1MEN1KMT2ACDC25BMALT1 | |
| SCHEMBL20046960 | 0.78 | IDO1 (0.52) | HKDC1MEN1KMT2AMALT1MAPT | |
| Anthraquinone SCHEMBL27847594 | 0.76 | CDC25B (0.75) | MEN1KMT2ACDC25BMALT1MAPT | |
| SCHEMBL6500778 | 0.76 | ALDH1A1 (0.44) | HKDC1MEN1KMT2ACDC25BMALT1 | |
| SCHEMBL6239008 | 0.76 | ALDH1A1 (0.46) | HKDC1MEN1KMT2AMALT1MAPT | |
| SCHEMBL9126138 | 0.76 | P2RX7 (0.55) | HKDC1MEN1KMT2ACDC25BMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022205111-A1 | METHOD FOR PREPARING EXATECAN DERIVATIVE, AND INTERMEDIATE THEREOF | 上海复旦张江生物医药股份有限公司 | 2022-10-06 | — | — | WO | claimed |