Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20044462 | 0.93 | SMN1; SMN2 (0.44) | KMT2AMEN1POLBKDM4EALDH1A1 | |
| SCHEMBL20043953 | 0.92 | PDE4B (0.42) | KDM4EALDH1A1LMNATP53TSHR | |
| SCHEMBL20044407 | 0.92 | TP53 (0.37) | KMT2AMEN1POLBALDH1A1TP53 | |
| SCHEMBL20044741 | 0.91 | KMT2A (0.38) | KMT2AMEN1POLBKDM4EALDH1A1 | |
| SCHEMBL20044723 | 0.90 | ALDH1A1 (0.39) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL20044756 | 0.90 | ALOX15 (0.36) | ALDH1A1TP53SMN1; SMN2P2RX7TSHR | |
| SCHEMBL20044127 | 0.90 | SLC6A2 (0.42) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL20044749 | 0.90 | TP53 (0.38) | KMT2AMEN1ALDH1A1HTR1DHTR1B | |
| SCHEMBL20044340 | 0.90 | TP53 (0.38) | KMT2AMEN1TP53 | |
| SCHEMBL20044742 | 0.89 | TUBB4A (0.39) | KMT2AMEN1POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220127229-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2022-04-28 | — | — | US | disclosed |
| US-11180453-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200347017-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2020-11-05 | — | — | US | disclosed |
| US-10654804-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2020-05-19 | — | — | US | disclosed |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2018-04-12 | — | — | US | disclosed |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | KMT2A 1699/4885MEN1 3340/4885POLB 3194/4885 |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | KMT2A 1699/4885MEN1 3340/4885POLB 3194/4885 |
| US-10654804-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | KMT2A 1699/4885MEN1 3340/4885POLB 3194/4885 |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | KMT2A 1693/4885MEN1 3362/4885POLB 3164/4885 |
| US-20220127229-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | KMT2A 1699/4885MEN1 3340/4885POLB 3194/4885 |
| US-20200347017-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | KMT2A 1699/4885MEN1 3340/4885POLB 3194/4885 |
| US-11180453-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | KMT2A 1699/4885MEN1 3340/4885POLB 3194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.