Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480303 | 0.92 | ALDH1A1 (0.36) | ALDH1A1ARAHRTSHRTRPV4 | |
| SCHEMBL13868310 | 0.85 | CD44 (0.41) | ALDH1A1ARTSHRTRPV4S1PR3 | |
| SCHEMBL23754017 | 0.83 | TRPV4 (0.39) | ALDH1A1ARTSHRTRPV4SLC22A12 | |
| SCHEMBL6948318 | 0.82 | TSHR (0.41) | ALDH1A1ARTSHRTRPV4S1PR3 | |
| SCHEMBL1343876 | 0.80 | TSHR (0.39) | ALDH1A1TSHRS1PR3 | |
| SCHEMBL30702008 | 0.80 | TSHR (0.39) | ALDH1A1TSHRS1PR3 | |
| SCHEMBL119203 | 0.79 | TSHR (0.50) | ALDH1A1ARTSHRTRPV4 | |
| SCHEMBL1343737 | 0.78 | TSHR (0.41) | ALDH1A1TSHRS1PR3 | |
| SCHEMBL18179223 | 0.78 | TRPV4 (0.45) | ALDH1A1ARTSHRTRPV4SLC22A12 | |
| SCHEMBL24252420 | 0.77 | CD44 (0.38) | ALDH1A1ARTSHRTRPV4SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858707-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2018068017-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF RAS AND METHODS OF USE THEREOF | ARAXES PHARMA LLC (US) | 2018-04-12 | — | — | WO | disclosed |