Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343876 | 1.00 | TSHR (0.39) | TSHRMEN1KMT2ATTRALB | |
| SCHEMBL1343737 | 0.93 | TSHR (0.41) | TSHRMEN1KMT2ATTRALB | |
| SCHEMBL4203403 | 0.85 | TSHR (0.46) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL119203 | 0.84 | TSHR (0.50) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5945887 | 0.82 | TSHR (0.48) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL23754017 | 0.80 | TRPV4 (0.39) | TSHRL3MBTL1ALDH1A1MAOB | |
| SCHEMBL12414780 | 0.80 | TSHR (0.41) | TSHRMEN1KMT2ATTRALB | |
| SCHEMBL1852407 | 0.80 | MEN1 (0.39) | TSHRMEN1KMT2ATTRALB | |
| SCHEMBL20045535 | 0.80 | ALDH1A1 (0.36) | TSHRALDH1A1S1PR3 | |
| SCHEMBL178611 | 0.80 | TRPV4 (0.45) | TSHREGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565574-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-06-11 | — | — | EP | disclosed |
| CN-119731159-A | SARS-CoV2 main proteinase inhibitor | 吉利德科学公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |