SCHEMBL2004652

SCHEMBL2004652

O=c1[nH]c(-c2ccccc2)c(-c2ccccc2)[nH]c1=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.71
ALDH1A1 P00352 2/20 0.71
PLA2G10 O15496 1/20 0.71
GAA P10253 1/20 0.71
HPGD P15428 1/20 0.71
HSD17B10 Q99714 1/20 0.71
SERPINE1 P05121 1/20 0.59
KMT2A Q03164 1/20 0.52
GRIN2D O15399 2/20 0.50
GRIN3B O60391 2/20 0.50
GRIN1 Q05586 2/20 0.50
GRIN2A Q12879 2/20 0.50
GRIN2B Q13224 2/20 0.50
GRIN2C Q14957 2/20 0.50
GRIN3A Q8TCU5 2/20 0.50
HSD11B1 P28845 1/20 0.46
NOTUM Q6P988 1/20 0.44
GSK3B P49841 1/20 0.44
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8442953 0.83 ALDH1A1 (1.00) KDM4EALDH1A1PLA2G10GAAHPGD
SCHEMBL854581 0.75 SERPINE1 (1.00) KDM4EALDH1A1PLA2G10GAAHPGD
SCHEMBL29031883 0.75 SERPINE1 (0.67) KDM4EALDH1A1PLA2G10GAAHPGD
SCHEMBL29639174 0.75 SERPINE1 (0.67) KDM4EALDH1A1PLA2G10GAAHPGD
SCHEMBL12323808 0.74 SERPINE1 (0.65) KDM4EALDH1A1PLA2G10GAAHPGD
SCHEMBL31047679 0.74 SERPINE1 (0.65) KDM4EALDH1A1PLA2G10GAAHPGD
SCHEMBL31047669 0.74 SERPINE1 (0.65) KDM4EALDH1A1PLA2G10GAAHPGD
SCHEMBL25148608 0.73 KDM4E (0.51) KDM4EALDH1A1PLA2G10GAAHPGD
SCHEMBL7038229 0.72 ALDH1A1 (0.56) KDM4EALDH1A1PLA2G10GAAHPGD
SCHEMBL6422263 0.70 KDM4E (0.54) KDM4EALDH1A1PLA2G10GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9653692-B2 Light-emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-16 US disclosed
US-20160155960-A1 Light-Emitting Device and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-06-02 US disclosed
US-9257657-B2 Light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-02-09 US disclosed
US-8889266-B2 Organometallic complex, and light-emitting element, light-emitting device and electronic-device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-11-18 US disclosed
EP-1869059-B1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE USING THE ORGANOMETALLIC COMPLEX SEMICONDUCTOR ENERGY LAB (JP) 2014-04-23 EP disclosed
US-7960038-B2 Light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-06-14 US disclosed
US-20090015143-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device and Electronic- Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-15 US disclosed
US-20060263636-A1 Light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2006-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090015143-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device and Electronic- Device Using the Organometallic Complex LIG3, CRY1, MCM3 KDM4E 2538/4885ALDH1A1 1016/4885PLA2G10 4236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.