Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766596 | 0.78 | MAPT (0.55) | KDM4EPLA2G10ALDH1A1GAAHPGD | |
| SCHEMBL3278733 | 0.78 | ESR1 (0.62) | KDM4EPLA2G10ALDH1A1GAAHPGD | |
| SCHEMBL27842932 | 0.77 | KDM4E (0.44) | KDM4EPLA2G10ALDH1A1GAAHPGD | |
| SCHEMBL30753519 | 0.71 | CHEK1 (0.52) | ALDH1A1GAAADKGSK3BMAPT | |
| SCHEMBL8442953 | 0.70 | ALDH1A1 (1.00) | KDM4EPLA2G10ALDH1A1GAAHPGD | |
| SCHEMBL114611 | 0.70 | PTGS2 (0.67) | GSK3BPTGS2 | |
| SCHEMBL2004652 | 0.70 | KDM4E (0.71) | KDM4EPLA2G10ALDH1A1GAAHPGD | |
| SCHEMBL135332 | 0.70 | GSK3B (0.56) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1572915 | 0.70 | ALDH1A1 (0.68) | KDM4EPLA2G10ALDH1A1GAAHPGD | |
| SCHEMBL9474080 | 0.69 | PTGS2 (0.64) | GSK3BPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890977-B2 | Warp-free pigment compositions comprising diaryldiketopyrrolo[3,4-c]pyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-05-10 | — | — | US | disclosed |
| EP-0952183-B1 | Warp free pigment compositions containing diaryl-diketopyrrolo 3,4c pyrroles | CIBA SC HOLDING AG (CH) | 2005-02-23 | — | — | EP | disclosed |
| US-20040092627-A1 | Warp-free pigment compositons comprising diaryldiketopyrrolo[3,4-c]pyrroles | FLANDRIN FRANCK REY (FR) | 2004-05-13 | — | — | US | disclosed |
| US-6409956-B1 | PARTIALLY CRYSTALLINE PLASTICS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-25 | — | — | US | disclosed |
| EP-0952183-A1 | Warp free pigment compositions containing diaryl-diketopyrrolo 3,4c pyrroles | Ciba SC Holding AG (CH) | 1999-10-27 | — | — | EP | disclosed |