Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 12/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.56 |
| ▸ | TUBB | P07437 | 7/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299632 | 1.00 | CYP1A1 (0.58) | CYP1A1CYP1A2CYP1B1GAAHTT | |
| SCHEMBL30887916 | 1.00 | CYP1A1 (0.58) | CYP1A1CYP1A2CYP1B1GAAHTT | |
| SCHEMBL20376311 | 0.89 | TUBB1 (0.54) | CYP1A1CYP1A2CYP1B1GAAHTT | |
| SCHEMBL9763615 | 0.87 | TUBB1 (0.55) | CYP1A1CYP1A2CYP1B1GAAHTT | |
| SCHEMBL9763608 | 0.87 | TUBB1 (0.55) | CYP1A1CYP1A2CYP1B1GAAHTT | |
| SCHEMBL14007277 | 0.86 | MAPT (0.49) | CYP1A1CYP1A2CYP1B1GAAHTT | |
| SCHEMBL1457517 | 0.86 | ABL1 (0.59) | CYP1A2GAAHTTKDM4EHPGD | |
| SCHEMBL807443 | 0.86 | ABL1 (0.59) | CYP1A2GAAHTTKDM4EHPGD | |
| SCHEMBL29603846 | 0.86 | ABL1 (0.59) | CYP1A2GAAHTTKDM4EHPGD | |
| SCHEMBL12963108 | 0.84 | TUBB1 (0.59) | CYP1A1CYP1A2CYP1B1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2003968-A2 | COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PRODUCTS, SO INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF | Leschot Sanhueza, Andres Antonio (CL) | 2008-12-24 | — | — | EP | claimed |
| US-20070232495-A1 | Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof | NAPPA ALVARO O | 2007-10-04 | — | — | US | claimed |
| WO-2007110801-A2 | COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PORDUCTS, INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF | LESCHOT SANHUEZA ANDRES ANTONI (CL) | 2007-10-04 | — | — | WO | claimed |
| US-20170137446-A1 | METHOD OF PREPARING AROMATIC COMPOUNDS FROM LIGNIN | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-05-18 | — | — | US | disclosed |
| EP-1927889-B1 | Lithographic printing plate precursor | FUJIFILM CORP (JP) | 2014-06-25 | — | — | EP | disclosed |
| US-20110218343-A1 | SMALL MOLECULE INHIBITORS OF ROTAMASE ENZYME ACTIVITY | GLIAMED, INC. (US) | 2011-09-08 | — | — | US | disclosed |
| US-7960570-B2 | Small molecule inhibitors of rotamase enzyme activity | GLIAMED, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| US-20100145071-A1 | SMALL MOLECULE INHIBITORS OF ROTAMASE ENZYME ACTIVITY | GLIAMED, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| EP-1433781-B1 | Pyrrolidine carboxylic acid derivatives | MGI GP INC (US) | 2010-02-24 | — | — | EP | disclosed |
| US-7652060-B2 | Neurotrophic N-glyoxyl-prolyl ester compounds e.g. 3-phenyl-1-propyl (2S)-1-(3,3-dimethyl-1,2-dioxopentyl)-2-pyrrolidinecarboxylate; non-immunosuppressive; side effect reduction; neurodegenerative diseases | Glia Med, Inc (US) | 2010-01-26 | — | — | US | disclosed |
| US-20090043109-A1 | ASYMMETRIC ONE- AND TWO-PHOTON FLUOROPHORES FOR SIMULTANEOUS DETECTION OF MULTIPLE ANALYTES USING A COMMON EXCITATION SOURCE | SENSOPATH TECHNOLOGIES, INC. | 2009-02-12 | — | — | US | disclosed |
| US-5196422-A | Antiinflammatory agents, antiallergens | ICI PHARMA (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5089513-A | Antiinflammatory agents; antiallergens; asthma; side effect reduction | ICI PHARMA (FR) | 1992-02-18 | — | — | US | disclosed |
| US-5089639-A | N-CYCLOALKYLALKYLAMINES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT AND THEIR SYNTHESIS INTERMEDIATES | JOUVEINAL S.A. (FR) | 1992-02-18 | — | — | US | disclosed |
| US-5034419-A | Psychological disorders or gastrointestinal disorders | L'OREAL (FR) | 1991-07-23 | — | — | US | disclosed |
| EP-0351194-A2 | Thiazole derivatives having a 5-lipoxygenase-inhibiting activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-17 | — | — | EP | disclosed |
| US-4704462-A | PLATELET-ACTIVATING FACTOR | MERCK & CO., INC. (US) | 1987-11-03 | — | — | US | disclosed |
| US-4687727-A | Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition | FUJI PHOTO FILM CO., LTD. (JP) | 1987-08-18 | — | — | US | disclosed |
| US-4511645-A | ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR | FUJI PHOTO FILM CO., LTD. (JP) | 1985-04-16 | — | — | US | disclosed |
| EP-0104863-A2 | Light-sensitive planographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 1984-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145071-A1 | SMALL MOLECULE INHIBITORS OF ROTAMASE ENZYME ACTIVITY | FKBP8, FKBP1A, FKBP2 | CYP1A1 3559/4885CYP1A2 3659/4885CYP1B1 2852/4885 |
| US-20070232495-A1 | Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof | C5, PNN, NQO1 | CYP1A1 444/4885CYP1A2 966/4885CYP1B1 904/4885 |
| US-20170137446-A1 | METHOD OF PREPARING AROMATIC COMPOUNDS FROM LIGNIN | DDT, PAH, PNPO | CYP1A1 25/4885CYP1A2 41/4885CYP1B1 88/4885 |
| US-20090043109-A1 | ASYMMETRIC ONE- AND TWO-PHOTON FLUOROPHORES FOR SIMULTANEOUS DETECTION OF MULTIPLE ANALYTES USING A COMMON EXCITATION SOURCE | ALDH1B1, ALDH2, ALDH3A1 | CYP1A1 1058/4885CYP1A2 2117/4885CYP1B1 731/4885 |
| US-20110218343-A1 | SMALL MOLECULE INHIBITORS OF ROTAMASE ENZYME ACTIVITY | FKBP8, FKBP1A, FKBP2 | CYP1A1 3559/4885CYP1A2 3659/4885CYP1B1 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.