SCHEMBL2005047

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2010870	0.94	TACR3 (0.48)	TACR3KCNH2TACR1NAAASMO
	SCHEMBL2006915	0.92	DRD2 (0.47)	DRD2DRD3TACR3SMOGHSR
	SCHEMBL2012548	0.90	TACR3 (0.49)	TACR3KCNH2TACR1NAAASMO
	SCHEMBL2005920	0.90	TACR3 (0.47)	TACR3KCNH2TACR1NAAASMO
	SCHEMBL4685415	0.90	SMO (0.52)	TACR3KCNH2TACR1NAAASMO
	SCHEMBL2012053	0.90	TACR3 (0.47)	TACR3KCNH2TACR1NAAASMO
	SCHEMBL2004027	0.90	NAAA (0.43)	TACR3KCNH2TACR1NAAASMO
	SCHEMBL2004071	0.89	L3MBTL1 (0.48)	ALDH1A1SMN1; SMN2GAAL3MBTL1PTGDR2
	SCHEMBL2007493	0.89	TACR3 (0.45)	TACR3KCNH2TACR1NAAASMO
	SCHEMBL2004262	0.89	SMO (0.53)	TACR3KCNH2TACR1NAAASMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.