Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | USP19 | O94966 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12745077 | 0.84 | KMT2A (0.47) | PDE7BPOLBRAB9AMAPK14ALDH1A1 | |
| SCHEMBL20051408 | 0.82 | MAPK14 (0.54) | CYP2C9CYP2C19RECQLRAB9ANPC1 | |
| SCHEMBL3800131 | 0.78 | CA2 (0.46) | POLBRAB9ANPC1ALDH1A1KCNJ1 | |
| Hydrochloric Acid SCHEMBL29932050 | 0.76 | PDE7B (0.35) | PDE7BPOLBRAB9ANPC1MAPK14 | |
| SCHEMBL21690928 | 0.75 | CYP2C19 (0.53) | CYP2C9CYP2C19RECQLPOLBRAB9A | |
| SCHEMBL20051405 | 0.75 | RAB9A (0.66) | CYP2C9CYP2C19POLBRAB9ANPC1 | |
| SCHEMBL21637775 | 0.75 | POLB (0.47) | PDE7BPOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL12337188 | 0.74 | CHRM4 (0.42) | CHRM4 | |
| SCHEMBL27404895 | 0.74 | HTR2C (0.49) | CYP2C9CYP2C19RAB9ANPC1ALDH1A1 | |
| SCHEMBL20563946 | 0.73 | LMNA (0.40) | RAB9ANPC1ALDH1A1SMN1; SMN2KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11234914-B2 | Monosubstituted urea derivatives as a self-tanning substance | MERCK PATENT GMBH (DE) | 2022-02-01 | — | — | US | disclosed |
| EP-3522993-B1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2021-04-07 | — | — | EP | disclosed |
| US-20200038304-A1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
| WO-2018065358-A1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11234914-B2 | Monosubstituted urea derivatives as a self-tanning substance | SLC14A1, TYR, UROD | CYP2C9 952/4885CYP2C19 456/4885PDE7B 1483/4885 |
| US-20200038304-A1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | SLC14A1, TYR, UROD | CYP2C9 952/4885CYP2C19 456/4885PDE7B 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.