Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052258 | 0.78 | BACE1 (0.42) | PPARAKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL20052222 | 0.78 | BACE1 (0.42) | PPARAKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL30744070 | 0.78 | KDM4E (0.45) | PPARAKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL28249954 | 0.78 | KDM4E (0.45) | PPARAKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL11556307 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1ALOX5GAAMAPT | |
| SCHEMBL18979298 | 0.73 | ESR1 (0.42) | KDM4EALDH1A1GAAMAPTESR1 | |
| SCHEMBL3808251 | 0.71 | CYP4F2 (0.45) | PPARAKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL20052268 | 0.70 | ESR1 (0.35) | PPARAKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL13813112 | 0.70 | DRD2 (0.41) | PPARAKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL8160238 | 0.69 | HSD17B1 (0.44) | ALDH1A1MAPTALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |