Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052258 | 0.90 | BACE1 (0.42) | ESR1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL20052222 | 0.83 | BACE1 (0.42) | ESR1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL13671875 | 0.76 | KDM4E (0.38) | ESR1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL63352 | 0.72 | BACE1 (0.54) | KDM4EALDH1A1ALOX5GAAMAPT | |
| SCHEMBL64008 | 0.72 | FOLH1 (0.33) | BACE1 | |
| SCHEMBL29362192 | 0.72 | FOLH1 (0.33) | BACE1 | |
| SCHEMBL20052124 | 0.70 | ESR1 (0.41) | ESR1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL20052233 | 0.70 | PPARA (0.39) | ESR1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL12235091 | 0.68 | CA2 (0.59) | ESR1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL13761460 | 0.67 | TRPA1 (0.45) | KDM4EALDH1A1ALOX5GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |