Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052258 | 0.93 | BACE1 (0.42) | BACE1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL20052268 | 0.83 | ESR1 (0.35) | BACE1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL63352 | 0.82 | BACE1 (0.54) | BACE1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL20052233 | 0.78 | PPARA (0.39) | BACE1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL20052124 | 0.75 | ESR1 (0.41) | BACE1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL13761460 | 0.72 | TRPA1 (0.45) | BACE1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL26239766 | 0.72 | TYR (0.47) | BACE1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL5871273 | 0.71 | KDM4E (0.52) | BACE1KDM4EALDH1A1ALOX5GAA | |
| SCHEMBL25751730 | 0.71 | ESR1 (0.48) | KDM4EALDH1A1GAAMAPTESR1 | |
| SCHEMBL26239744 | 0.69 | TP53 (0.50) | KDM4EALDH1A1ALOX5MAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |