Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 6/20 | 0.44 |
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15462669 | 1.00 | MMP9 (0.44) | MMP9MMP2MMP13MMP1MMP3 | |
| SCHEMBL20355927 | 1.00 | MMP9 (0.44) | MMP9MMP2MMP13MMP1MMP3 | |
| SCHEMBL19944856 | 0.82 | ALDH1A1 (0.41) | MMP9MMP2MMP13MMP3ALDH1A1 | |
| SCHEMBL19944858 | 0.81 | PSMB8 (0.46) | MMP9MMP2MMP13ALDH1A1TSHR | |
| SCHEMBL4172106 | 0.76 | TDP1 (0.54) | MMP9MMP2MMP13MMP1MMP3 | |
| SCHEMBL8451620 | 0.75 | MMP2 (0.51) | MMP9MMP2MMP13MMP3ALDH1A1 | |
| SCHEMBL21538660 | 0.75 | MMP9 (0.69) | MMP9MMP2MMP13MMP1MMP3 | |
| SCHEMBL28216417 | 0.75 | MMP9 (0.69) | MMP9MMP2MMP13MMP1MMP3 | |
| SCHEMBL4174025 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TSHRCA2 | |
| SCHEMBL4174029 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |