Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.51 |
| ▸ | MMP13 | P45452 | 6/20 | 0.51 |
| ▸ | MMP3 | P08254 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9088931 | 0.84 | MMP9 (0.44) | MMP2MMP13MMP3MMP9ALDH1A1 | |
| SCHEMBL9088936 | 0.84 | MMP9 (0.44) | MMP2MMP13MMP3MMP9ALDH1A1 | |
| SCHEMBL8448550 | 0.82 | MMP2 (0.49) | MMP2MMP13MMP3MMP9ALDH1A1 | |
| SCHEMBL8445714 | 0.82 | MMP2 (0.64) | MMP2MMP13MMP3MMP9ALDH1A1 | |
| SCHEMBL7674853 | 0.81 | SMN1; SMN2 (0.42) | MMP2MMP13MMP9ALDH1A1TSHR | |
| SCHEMBL8450035 | 0.81 | MMP9 (0.58) | MMP2MMP13MMP3MMP9ALDH1A1 | |
| SCHEMBL8449978 | 0.81 | MMP9 (0.58) | MMP2MMP13MMP3MMP9ALDH1A1 | |
| SCHEMBL8446644 | 0.79 | MMP9 (0.70) | MMP2MMP13MMP3MMP9ALDH1A1 | |
| SCHEMBL19944858 | 0.79 | PSMB8 (0.46) | MMP2MMP13MMP9ALDH1A1TSHR | |
| SCHEMBL30988973 | 0.77 | TDP1 (0.48) | MMP2MMP13MMP3MMP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |