Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412978 | 1.00 | CASR (0.51) | CASRMTNR1AMTNR1BTAAR1ALDH1A1 | |
| SCHEMBL7413751 | 0.89 | CASR (0.47) | CASRMTNR1AMTNR1BTAAR1 | |
| SCHEMBL7405335 | 0.89 | CASR (0.47) | CASRMTNR1AMTNR1BTAAR1 | |
| SCHEMBL26152585 | 0.87 | MTNR1A (0.61) | CASRMTNR1AMTNR1BTAAR1ALDH1A1 | |
| SCHEMBL5311110 | 0.85 | MTNR1A (0.62) | CASRMTNR1AMTNR1BTAAR1ALDH1A1 | |
| SCHEMBL6209733 | 0.84 | ALDH1A1 (0.64) | TAAR1ALDH1A1 | |
| SCHEMBL11081355 | 0.83 | AOC3 (0.54) | CASRMTNR1AMTNR1BTAAR1ALDH1A1 | |
| SCHEMBL7411654 | 0.82 | AOC3 (0.48) | CASRMTNR1AMTNR1BTAAR1ALDH1A1 | |
| SCHEMBL22335122 | 0.81 | CASR (0.58) | CASRMTNR1AMTNR1BTAAR1ALDH1A1 | |
| SCHEMBL7169569 | 0.79 | AOC3 (0.56) | CASRMTNR1AMTNR1BMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944589-B2 | Cycloproplyamine derivatives useful as inhibitors of histone demethylases KDM1A | ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2018-04-17 | — | — | US | disclosed |