Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452354 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TSHRLTA4HTAAR1POLB | |
| SCHEMBL7412978 | 0.84 | CASR (0.51) | ALDH1A1TAAR1 | |
| SCHEMBL20052924 | 0.84 | CASR (0.51) | ALDH1A1TAAR1 | |
| SCHEMBL15286352 | 0.83 | GABBR2 (0.50) | TAAR1 | |
| SCHEMBL29048475 | 0.82 | ALDH1A1 (0.43) | ALDH1A1TAAR1L3MBTL1CNR2 | |
| SCHEMBL6211904 | 0.81 | L3MBTL1 (0.55) | ALDH1A1TSHRTAAR1L3MBTL1NPC1 | |
| SCHEMBL17996029 | 0.80 | GABBR2 (0.47) | TAAR1 | |
| SCHEMBL11079771 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TSHRTAAR1L3MBTL1SLC6A2 | |
| SCHEMBL29048454 | 0.79 | GABBR2 (0.51) | TSHRTAAR1SLC6A2SLC6A4CNR2 | |
| SCHEMBL9872486 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRTAAR1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234096-A1 | Tetrahydroisoquinoline derivatives | BAYER HEALTHCARE AG (DE) | 2005-10-20 | — | — | US | disclosed |
| US-6956040-B2 | Oxazolidinone piperazinyl derivatives as potential antimicrobials | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-18 | — | — | US | disclosed |
| EP-1507763-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | Bayer HealthCare AG (DE) | 2005-02-23 | — | — | EP | disclosed |
| US-20040254162-A1 | Oxazolidinone derivatives as antimicrobials | RANBAXY LABORATORIES LIMITED (IN) | 2004-12-16 | — | — | US | disclosed |
| WO-2003097607-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2003-11-27 | — | — | WO | disclosed |
| US-20030119817-A1 | Oxazolidinone derivatives as potential antimicrobials | MEHTA ANITA (IN) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119817-A1 | Oxazolidinone derivatives as potential antimicrobials | OXA1L, PDK4, SDHA | ALDH1A1 973/4885TSHR 1336/4885LTA4H 1714/4885 |
| US-20040254162-A1 | Oxazolidinone derivatives as antimicrobials | PPARD, PDK4, OXA1L | ALDH1A1 934/4885TSHR 1486/4885LTA4H 1947/4885 |
| US-20050234096-A1 | Tetrahydroisoquinoline derivatives | PPARD, PPARG, PPARA | ALDH1A1 2218/4885TSHR 1402/4885LTA4H 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.