Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17457734 | 0.86 | ITGB3 (0.37) | ITGB3ITGA2B | |
| SCHEMBL16119478 | 0.86 | ITGB3 (0.37) | ITGB3ITGA2B | |
| SCHEMBL20053206 | 0.79 | SMYD3 (0.38) | — | |
| SCHEMBL22667379 | 0.79 | NAMPT (0.39) | — | |
| SCHEMBL23837376 | 0.79 | SMYD3 (0.34) | — | |
| SCHEMBL20370991 | 0.79 | KDM1A (0.32) | — | |
| SCHEMBL18797980 | 0.78 | NAMPT (0.35) | — | |
| SCHEMBL22667381 | 0.78 | MTNR1A (0.41) | — | |
| SCHEMBL15869975 | 0.78 | — | — | |
| SCHEMBL19228009 | 0.77 | DRD2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944658-B2 | Beta-lactamase inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2018-04-17 | — | — | US | disclosed |