Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSH | P09668 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 6/20 | 0.34 |
| ▸ | REN | P00797 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PEPD | P12955 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26723980 | 1.00 | CTSL (0.40) | CTSLCTSBCTSHCTSKRAB9A | |
| SCHEMBL25873103 | 1.00 | CTSL (0.40) | CTSLCTSBCTSHCTSKRAB9A | |
| SCHEMBL26030704 | 0.95 | CTSL (0.39) | CTSLCTSBCTSHCTSKRAB9A | |
| SCHEMBL13910188 | 0.84 | TSHR (0.46) | RAB9ATSHRPEPDPOLB | |
| SCHEMBL1684095 | 0.84 | TSHR (0.46) | RAB9ATSHRPEPDPOLB | |
| SCHEMBL278662 | 0.84 | TSHR (0.46) | RAB9ATSHRPEPDPOLB | |
| SCHEMBL24283107 | 0.82 | RAB9A (0.36) | CTSLCTSBCTSHCTSKRAB9A | |
| SCHEMBL26727435 | 0.80 | CTSL (0.40) | CTSLCTSBCTSHCTSKRAB9A | |
| SCHEMBL25873736 | 0.80 | CTSL (0.40) | CTSLCTSBCTSHCTSKRAB9A | |
| SCHEMBL4638246 | 0.79 | FKBP1A (0.46) | RAB9ATSHRKDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943609-B2 | Protein-polymer-drug conjugates | MERSANA THERAPEUTICS, INC. (US) | 2018-04-17 | — | — | US | disclosed |