Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9974834 | 0.82 | KDM4E (0.47) | MAPTPOLBALDH1A1KMT2ANPSR1 | |
| SCHEMBL9974833 | 0.81 | POLB (0.45) | MAPTPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL9974823 | 0.71 | MAPT (0.53) | MAPTALDH1A1KMT2AMEN1HTR3A | |
| SCHEMBL9974832 | 0.70 | KDM4E (0.49) | MAPTPOLBALDH1A1KMT2ANPSR1 | |
| SCHEMBL29574988 | 0.66 | ALDH1A1 (0.61) | MAPTPOLBALDH1A1KMT2ANPSR1 | |
| SCHEMBL25733860 | 0.66 | ALDH1A1 (0.61) | MAPTPOLBALDH1A1KMT2ANPSR1 | |
| SCHEMBL28370067 | 0.65 | THRA (0.57) | MAPTPOLBALDH1A1PTGS2 | |
| SCHEMBL9974831 | 0.65 | KDM4E (0.51) | MAPTPOLBALDH1A1KMT2ANPSR1 | |
| SCHEMBL4692026 | 0.63 | ALDH1A1 (0.76) | MAPTPOLBALDH1A1NPSR1KDM4E | |
| SCHEMBL573394 | 0.63 | PTGS2 (0.58) | POLBALDH1A1KMT2AMEN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944638-B2 | Indoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND US (IE) | 2018-04-17 | — | — | US | disclosed |