Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 3/20 | 0.37 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16248536 | 0.89 | NAMPT (0.40) | NAMPTLMNAPKMALBNMT2 | |
| SCHEMBL17589403 | 0.86 | LMNA (0.39) | NAMPTLMNAPKMALBNMT2 | |
| SCHEMBL22022417 | 0.85 | NAMPT (0.38) | NAMPTLMNAPKMALBNMT2 | |
| SCHEMBL26773565 | 0.85 | NAMPT (0.41) | NAMPTLMNAPKMALBNMT2 | |
| SCHEMBL24119973 | 0.82 | NAMPT (0.39) | NAMPTLMNAPKMALBNMT2 | |
| SCHEMBL18879466 | 0.82 | NAMPT (0.39) | NAMPTLMNAPKMALBNMT2 | |
| SCHEMBL14952664 | 0.82 | ALDH1A1 (0.41) | NAMPTLMNAPKMALBNMT2 | |
| SCHEMBL18513227 | 0.80 | NMT1 (0.54) | NMT2NMT1NOD1GLP1R | |
| SCHEMBL24818366 | 0.79 | NAMPT (0.52) | NAMPTLMNAPKMCNR1HPGD | |
| SCHEMBL10345306 | 0.79 | NAMPT (0.52) | NAMPTLMNAPKMCNR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943604-B2 | Targeted therapeutic nucleosides and their use | IONIS PHARMACEUTICALS, INC. (US) | 2018-04-17 | — | — | US | disclosed |