Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16248536 | 0.97 | NAMPT (0.40) | LMNAPKMNMT2NMT1NAMPT | |
| SCHEMBL14952664 | 0.90 | ALDH1A1 (0.41) | LMNAPKMNMT2NMT1NAMPT | |
| SCHEMBL21913856 | 0.87 | ALDH1A1 (0.43) | ALDH1A1ALBTSHRMEN1KMT2A | |
| SCHEMBL20053466 | 0.86 | NAMPT (0.39) | LMNAPKMNMT2NMT1NAMPT | |
| SCHEMBL25132901 | 0.84 | ALB (0.37) | LMNAPKMNAMPTCNR1ALDH1A1 | |
| SCHEMBL25132903 | 0.84 | ALB (0.37) | LMNAPKMNAMPTCNR1ALDH1A1 | |
| SCHEMBL25132500 | 0.84 | ALB (0.37) | LMNAPKMNAMPTCNR1ALDH1A1 | |
| SCHEMBL20053467 | 0.84 | NMT2 (0.41) | LMNAPKMNMT2NMT1NAMPT | |
| SCHEMBL26773565 | 0.84 | NAMPT (0.41) | LMNAPKMNMT2NMT1NAMPT | |
| SCHEMBL16409459 | 0.84 | CASP2 (0.51) | ALDH1A1NOD1ALBFAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160076032-A1 | COMPOSITIONS AND METHODS | ISIS PHARMACEUTICALS, INC. (US) | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160076032-A1 | COMPOSITIONS AND METHODS | FUT6, FUT5, GNE | LMNA 411/4885PKM 3234/4885NMT2 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.