Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | CPS1 | P31327 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053541 | 0.92 | SLC6A9 (0.41) | SLC6A9KCNH2HRH3GPR119CPS1 | |
| SCHEMBL15539463 | 0.90 | PIK3CA (0.39) | SLC6A9GPR119HTR2AHTR2CSCN7A | |
| SCHEMBL15539462 | 0.90 | PIK3CA (0.39) | SLC6A9GPR119HTR2AHTR2CSCN7A | |
| SCHEMBL15538764 | 0.90 | CHRM4 (0.40) | KCNH2GPR119SCN7ASCN5ASCN9A | |
| SCHEMBL20053539 | 0.87 | XDH (0.42) | SLC6A9KCNH2HRH3GPR119MTOR | |
| SCHEMBL20053607 | 0.87 | GPR119 (0.44) | KCNH2HRH3GPR119CPS1CHRM2 | |
| SCHEMBL16803742 | 0.86 | CNR2 (0.37) | GPR119SCN7ASCN5ASCN9APIK3CA | |
| SCHEMBL16777099 | 0.86 | PKM (0.40) | KCNH2GPR119HTR2CSCN7ASCN5A | |
| SCHEMBL21535011 | 0.85 | HTR2A (0.48) | KCNH2HRH3CPS1HTR2AHTR2C | |
| SCHEMBL15539342 | 0.84 | PIK3CA (0.43) | SLC6A9GPR119SCN9APIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |