Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.44 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197337 | 0.98 | HCRTR1 (0.45) | MEN1KMT2AHCRTR1HCRTR2RXFP3 | |
| SCHEMBL20054584 | 0.95 | MEN1 (0.45) | MEN1KMT2AHCRTR1HCRTR2RXFP3 | |
| SCHEMBL12488545 | 0.94 | ALDH1A1 (0.42) | MEN1KMT2AHCRTR1HCRTR2RXFP3 | |
| SCHEMBL2179845 | 0.94 | ALDH1A1 (0.42) | MEN1KMT2AHCRTR1HCRTR2RXFP3 | |
| SCHEMBL2193840 | 0.88 | HSD17B10 (0.53) | MEN1KMT2AHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL2195941 | 0.88 | HSD17B10 (0.53) | MEN1KMT2AHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL15125394 | 0.85 | FKBP1A (0.40) | MEN1KMT2AHCRTR1HCRTR2RXFP3 | |
| SCHEMBL27896406 | 0.84 | PORCN (0.39) | MEN1KMT2AHCRTR1HCRTR2RXFP3 | |
| SCHEMBL12489099 | 0.84 | ALDH1A1 (0.50) | MEN1KMT2AHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL2175697 | 0.84 | ALDH1A1 (0.50) | MEN1KMT2AHCRTR1HCRTR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |