Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3995663 | 1.00 | ALDH1A1 (0.43) | ALDH1A1ALOX15CYP3A4ESR1ESR2 | |
| SCHEMBL27390196 | 1.00 | ALDH1A1 (0.43) | ALDH1A1ALOX15CYP3A4ESR1ESR2 | |
| SCHEMBL27909852 | 0.82 | LTA4H (0.44) | ALDH1A1MAPK1KMT2AMAPTCYP2C9 | |
| SCHEMBL6017366 | 0.80 | ALDH1A1 (0.46) | ALDH1A1ALOX15CYP3A4ESR1ESR2 | |
| SCHEMBL12015995 | 0.79 | TSHR (0.48) | ALDH1A1CYP3A4ESR1ESR2CYP2D6 | |
| SCHEMBL10386424 | 0.78 | AKR1C3 (0.45) | ALDH1A1ALOX15CYP2D6KMT2AMAPT | |
| SCHEMBL7863860 | 0.77 | KMT2A (0.58) | MAPK1KMT2AHIF1A | |
| SCHEMBL7030622 | 0.77 | MAPK1 (0.46) | ALDH1A1ALOX15CYP3A4ESR1ESR2 | |
| SCHEMBL28606840 | 0.76 | ALDH1A1 (0.43) | ALDH1A1ALOX15CYP3A4ESR1ESR2 | |
| SCHEMBL127044 | 0.76 | ALDH1A1 (0.43) | ALDH1A1ALOX15CYP3A4ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599584-A1 | MODIFIED NITRILASES AND THEIR USE IN METHODS FOR THE PRODUCTION OF CARBOXYLIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2005-11-30 | — | — | EP | claimed |
| WO-2004076655-A1 | MODIFIED NITRILASES AND THEIR USE IN METHODS FOR THE PRODUCTION OF CARBOXYLIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-10 | — | — | WO | claimed |
| EP-0610049-B1 | Process for producing optically active alpha-hydroxycarboxylic acid having phenyl group | MITSUBISHI RAYON CO (JP) | 1999-11-03 | — | — | EP | claimed |
| EP-0610048-B1 | Process for producing optically active alpha-hydrocarboxylic acid having phenyl group | MITSUBISHI RAYON CO (JP) | 1999-09-22 | — | — | EP | claimed |
| US-5714357-A | Process for producing optically active α-hydroxycarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-02-03 | — | — | US | claimed |
| EP-0527553-B1 | Process for producing r(-)-mandelic acid and derivative thereof | NITTO CHEMICAL INDUSTRY CO LTD (JP) | 1997-05-07 | — | — | EP | claimed |
| US-5580765-A | A CULTURE PRODUCT OF A-HYDROXYNITRILE OR A MIXTURE OF ALDEHYDE AND PRUSSIC ACID | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-12-03 | — | — | US | claimed |
| EP-0610048-A2 | Process for producing optically active alpha-hydrocarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-10 | — | — | EP | claimed |
| EP-0610049-A2 | Process for producing optically active alpha-hydroxycarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-10 | — | — | EP | claimed |
| US-5296373-A | Stereoselective hydrolysis of mandelonitrile in neutral or basic aqueous medium | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-03-22 | — | — | US | claimed |
| EP-0527553-A1 | Process for producing r(-)-mandelic acid and derivative thereof | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-02-17 | — | — | EP | claimed |
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| US-9828594-B2 | Nitrilases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2017-11-28 | — | — | US | disclosed |
| US-20160355801-A1 | NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORPORATION | 2016-12-08 | — | — | US | disclosed |
| EP-0072482-A2 | (Thiono)(dithio)-phosphoric-(phosphonic)-acid esters, process for their preparation and their use as pesticides | BAYER AG (DE) | 1983-02-23 | — | — | EP | disclosed |
| US-4243814-A | TO PRODUCE ALPHA-AMINOACIDS USING A KETONE AND HYDROXIDE IONS | PASCAL ROBERT | 1981-01-06 | — | — | US | disclosed |
| US-4108883-A | DEWATERING AGENTS FOR WASTE TREATMENT | AMERICAN CYANAMID COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4044009-A | Pyrimidine alcohols and derivatives thereof | AMERICAN CYANAMID COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4007200-A | POLYMER INTERMEDIATE | AMERICAN CYANAMID COMPANY (US) | 1977-02-08 | — | — | US | disclosed |