Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20056482 | 0.80 | HSD17B1 (0.47) | HSD17B1HSD17B2ESR2SMN1; SMN2HDAC2 | |
| SCHEMBL5437372 | 0.79 | GAA (0.50) | GAASMN1; SMN2PDK2ACLYNUDT1 | |
| SCHEMBL17481527 | 0.77 | GAA (0.58) | GAASMN1; SMN2KCNMA1NUDT1KDM4E | |
| SCHEMBL16076888 | 0.75 | HSD17B1 (0.54) | HSD17B1HSD17B2ESR2PDK2 | |
| SCHEMBL3979604 | 0.73 | CA12 (0.53) | HSD17B1HSD17B2SMN1; SMN2PDK2ERCC1 | |
| SCHEMBL2102486 | 0.73 | P2RX1 (0.47) | GAASMN1; SMN2KCNMA1NUDT1LMNA | |
| SCHEMBL20652569 | 0.72 | GAA (0.50) | GAASMN1; SMN2SCN9ANUDT1KDM4E | |
| SCHEMBL7133296 | 0.72 | CES2 (0.61) | GAASCN9ANUDT1KDM4ELMNA | |
| SCHEMBL3979148 | 0.72 | ACMSD (0.59) | HSD17B1HSD17B2ERCC1ERCC4KDM4E | |
| SCHEMBL3978041 | 0.71 | ERCC1 (0.50) | HSD17B1HSD17B2ESR2ESR1ERCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970353-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-04-18 | — | — | EP | disclosed |